We noticed a difference right away -it was a slight difference but we did notice a difference (mostly in color) but then there didn't seem to be much of a change at all as about a month or two went by and then suddenly we saw a difference. It was almost like how my daughter's hemangioma grew. Hers started out very small and stayed small for awhile and then BAM it hit a growth spurt and grew quite large. Well it seemed that is what happened with the propanolol too. She was supposed to start being weaned off at around 9 months but we tried it and her H got larger so she is now 10 months and will be 1 at the end of August. She will continue taking the propanolol thru her first birthday and in Sept. her dermatologist wants to really try to start weaning again. Good luck! Oh and as TJ stated we also noticed a color change and a "flattening" effect right away.
Deep hemangioma on left eyebrow towards nose
Started propanolol Feb. 11th, 2010
Off of propanolol aprox. June 2011
Takes 3 doses per day at 1.3ml
2nd Weaning of prop. not a success back on it March 22. Only one dose of 1.3ml now Baby girl is 19 months old
Did Timolol gel for awhile, stopped, & back on - 4 years old.