superficial hemangioma treatments

ttn · #1 04-16-2009, 12:10 PM

My 6 weeks old daughter had 1 PDL treatment to a superficial hemangioma above her eye lid. We are seeing a hemangioma specialist (who is a surgeon & has not used propranolol for hemangioma) & a pediatric ophthalmologist.
My questions: We consulted with an adult dermatologist (no pediatric one on our area) & she suggested propranolol. She has never tried propranolol.
1.Where can I obtain information on propranolol dosage, how to wean off etc. She's 6 lbs-should she be monitored for low blood sugar & low blood pressure?
2. Should she begin propranolol while receiving PDL or wait and see results of laser treatments? Given the location of the hemangioma, I want to be as proactive as possible

missy · #2 04-17-2009, 12:23 AM

Someone will be along to answer your questions soon. In the meantime, could you post a photo? It's helpful to know what the size and exact location might be... will it grow to affect eyesight, etc.

Missy

nickbar · #3 04-17-2009, 05:12 PM

Hello,
This a very good and critical questions. I would highly recommend having these questions answered by a physician that is using the Propranolol and also does laser. Dr. Waner is one option.. email him via the "ask the expert" on the main page of this website. IF you need any help, please let me know.

Corinne

Tamia · #4 04-17-2009, 08:18 PM

The original New England Journal of Medicine article mentions the treatment dosage they used.
2 mg per kilogram per day.

http://content.nejm.org/cgi/content/full/358/24/2649

Also, there is a 30 day clinical trial on infants under 3 months currently being done in France. The dosages are also listed in their article.
30 days-propranolol treatment : 3 mg/kg 15 days + 4 mg/kg 15 days

http://www.clinicaltrials.gov/ct2/show/NCT00744185